Prof. Maren Schenke

My research focuses on the development of neuronal models derived from human induced pluripotent stem cells. By increasing the physiological relevance of these models, we can improve translation and generate findings that are more applicable to human biology. A key aspect of my work is to implement sex as a biological variable, for which sex hormones are essential. With this, we can generate models that account for sex differences, which are especially pronounced in neurodevelopmental disorders such as autism. We use these models to study how different diseases or neurotoxicants affect neuronal function and network development in a sex-specific manner. With this, we can develop more personalized and effective treatments for neurological conditions.